neurophysiology images 2001-05: 6-OHDA experiments

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overall view of rat brain, in parasagittal section, using myelin (Luxol fast blue) and neuronal (Nissl) stains
filename, dt_23_rat_parasagittal (format, JPEG)
file size, 0.09 MiB
size at 300 dpi, 97mm x 73mm/ 3.84" x 2.89"
date, 20 08 2005
to see the image full-size, click the thumbnail

tyrosine hydroxylase labelling of rat forebrain in horizontal section, with, from left, glomerular layers of OB, striatum, and Substantia Nigra
filename, dt_29_panTH_composite (format, JPEG)
file size, 0.15 MiB
size at 300 dpi, 97mm x 73mm/ 3.84" x 2.88"
date, 20 08 2005
to see the image full-size, click the thumbnail

summary figure showing tyrosine hydroxylase anatomy of the rat brain (below), and detail of the glomeruli of the olfactory bulb (top left)
filename, dt_panTH-6OHDA-mosaic (format, JPEG)
file size, 0.11 MiB
size at 300 dpi, 97mm x 77mm/ 3.84" x 3.03"
date, 20 08 2005
to see the image full-size, click the thumbnail

slide from reference series of tyrosine hydroxylase labelled coronal sections prepared from mouse hindbrain
filename, desktopTHatlas (format, JPEG)
file size, 0.11 MiB
size at 300 dpi, 97mm x 73mm/ 3.84" x 2.88"
date, 20 08 2005
to see the image full-size, click the thumbnail

brain of mouse in parasagittal section, showing tyrosine hydroxylase (brown) in SN, STN and striatum. Blue, myelin.
filename, dt_striatum_composite (format, JPEG)
file size, 0.09 MiB
size at 300 dpi, 97mm x 72mm/ 3.84" x 2.83"
date, 20 08 2005
to see the image full-size, click the thumbnail

detail from previous figure showing striatum and thalamus of mouse, showing tyrosine hydroxylase (brown) in striatum. Blue, myelin.
filename, dt_striatum (format, JPEG)
file size, 0.11 MiB
size at 300 dpi, 97mm x 77mm/ 3.84" x 3.04"
date, 20 08 2005
to see the image full-size, click the thumbnail

dark masses of the Substantia Nigra (lower centre) and the Subthalamic Nucleus (centre right) in the ventral midbrain, TH and LFB labels
filename, dt_midbrain_panTH (format, JPEG)
file size, 0.09 MiB
size at 300 dpi, 97mm x 73mm/ 3.84" x 2.88"
date, 20 08 2005
to see the image full-size, click the thumbnail

regions of ventrolateral rat midbrain in transverse section labelled immunohistochemically for Hu. Image by Tharushini Bowala.
filename, Hu_labeling_in_rat_mid (format, JPEG)
file size, 0.09 MiB
size at 300 dpi, 97mm x 77mm/ 3.84" x 3.06"
date, 20 08 2005
to see the image full-size, click the thumbnail

early experiment showing effect of previous unilateral 6-OHDA injection in striatum on the ipsilateral Substantia Nigra (top left)
filename, desktopTHmontage (format, JPEG)
file size, 0.07 MiB
size at 300 dpi, 97mm x 73mm/ 3.84" x 2.88"
date, 20 08 2005
to see the image full-size, click the thumbnail

the nigrostriatal tract, enlarged below, showing on the right the toxic effects of 6-OHDA administered within the striatum
filename, dt_fibres (format, JPEG)
file size, 0.13 MiB
size at 300 dpi, 97mm x 72mm/ 3.84" x 2.83"
date, 15 08 2005
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horizontal section of rat forebrain showing deficit of striatal tyrosine hydroxylase after ipsilateral midbrain forebrain bundle 6-OHDA, in model of PD
filename, dt-27-6OHDA-forebrain (format, JPEG)
file size, 0.1 MiB
size at 300 dpi, 97mm x 73mm/ 3.84" x 2.88"
date, 20 08 2005
to see the image full-size, click the thumbnail

horizontal section rat forebrain labelled for tyrosine hydroxylase after ipsilateral midbrain forebrain bundle 6-OHDA. Note effect on striatum but not OB
filename, dt-27-6OHDAuniOlfact (format, JPEG)
file size, 0.1 MiB
size at 300 dpi, 97mm x 73mm/ 3.84" x 2.88"
date, 20 08 2005
to see the image full-size, click the thumbnail

tyrosine hydroxylase phosphorylation variants: distribution in the rat hippocampus and midbrain. Parasagittal sections.
filename, TH-comparison_peroxidase (format, JPEG)
file size, 0.12 MiB
size at 300 dpi, 97mm x 73mm/ 3.84" x 2.9"
date, 20 08 2005
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distribution of tyrosine hydroxylase phosphorylation variants in rat olfactory bulb, striatum, Substantia Nigra and adrenal gland
filename, dt_29_TH_comparison (format, JPEG)
file size, 0.12 MiB
size at 300 dpi, 97mm x 73mm/ 3.84" x 2.88"
date, 20 08 2005
to see the image full-size, click the thumbnail

studies of tyrosine hydroxylase phosphorylation variants in the rat striatum
filename, desktop_TH_comparison (format, JPEG)
file size, 0.12 MiB
size at 300 dpi, 97mm x 73mm/ 3.84" x 2.88"
date, 20 08 2005
to see the image full-size, click the thumbnail

comparison of fluorescent image from two microscopes
filename, desktopmicroscope (format, JPEG)
file size, 0.12 MiB
size at 300 dpi, 97mm x 71mm/ 3.84" x 2.8"
date, 20 08 2005
to see the image full-size, click the thumbnail


thanks to David Ekholm in Järfälla for JAlbum. Version 5.2.2, using the skin Bioscience